Saturday, October 13, 2012

Pharmacology Of Benzquinamide

Indication Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously.
Pharmacodynamics Benzquinamide is an antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.
Mechanism of action The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Absorption Incomplete, with 33–39% bioavailability via the capsule and suppository routes, relative to the intramuscular route.
Volume of distribution Not Available
Protein binding Not Available
Metabolism Not Available
Route of elimination Not Available
Half life 1-1.6 hours (for all formulations)
Clearance Not Available
Toxicity Not Available

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