Indication | For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae. |
Pharmacodynamics | Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. |
Mechanism of action | During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. |
Absorption | Absorbed following oral administration. |
Volume of distribution | Not Available |
Protein binding | Not Available |
Metabolism | Not Available |
Route of elimination | Not Available |
Half life | Not Available |
Clearance | Not Available |
Toxicity | Not Available |
Saturday, October 13, 2012
Pharmacology Of Bacampicillin
Labels:
Pharmacology of Drugs,
UNCLASSIFIED
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